| 11/6 1:00 ET | At Kansas City | -9 | Jacksonville |
| 11/6 1:00 ET | At Minnesota | -6 | Detroit |
| 11/6 1:00 ET | At NY Giants | -2.5 | Philadelphia |
| 11/6 1:00 ET | Dallas | -7.5 | At Cleveland |
| 11/6 1:00 ET | At Miami | -3.5 | NY Jets |
| 11/6 1:00 ET | At Baltimore | -2 | Pittsburgh |
| 11/6 4:05 ET | New Orleans | -3.5 | At San Francisco |
| 11/6 4:05 ET | Carolina | -3 | At Los Angeles |
| 11/6 4:25 ET | At Green Bay | -7 | Indianapolis |
| 11/6 4:25 ET | At San Diego | -5 | Tennessee |
| 11/6 8:30 ET | At Oakland | -1 | Denver |
| 11/7 8:30 ET | At Seattle | -7 |
Buffalo |
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